Vol. 39 No. 6 (2022): DICIEMBRE
Original Article

Mortality in children with bacteremia due to Burkholderia cepacia: a systematic review.

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  • Maria Teresa Rosanova,
  • Pedro Serrano-Aguilar,
  • Leticia Rodriguez-Rodriguez,
  • Roberto Lede
Maria Teresa Rosanova
Hospital Juan P Garrahan, Buenos Aires
Bio
Pedro Serrano-Aguilar
Servicio de Evaluación de la Dirección del Servicio Canario de Salud (SESCS), Canarias, España
Leticia Rodriguez-Rodriguez
Fundación Instituto de Investigación Sanitaria de Canarias (FIISC), Canarias, España
Roberto Lede
Universidad abierta interamericana

Published 2023-01-26

Keywords

How to Cite

1.
Rosanova MT, Serrano-Aguilar P, Rodriguez-Rodriguez L, Lede R. Mortality in children with bacteremia due to Burkholderia cepacia: a systematic review. Rev. Chilena. Infectol. [Internet]. 2023 Jan. 26 [cited 2026 Apr. 27];39(6). Available from: https://revinf.cl/index.php/revinf/article/view/1575

Copyright (c) 2023 Maria Teresa Rosanova, Pedro Serrano-Aguilar, Leticia Rodriguez-Rodriguez, Roberto Lede

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Background: Bacteremia due to Burkolderia cepacia in children is considered a severe complication and associated with high mortality incidence. In order to know the level of mortality associated with it, this systematic review of the literature was carried out.

Methods: A search strategy was carried out with the keywords: “bacteremia by B cepacia and human” and “children” and “adolescents” as filters. Global frequency of mortality reported by the included studies was calculated and informed as median (Q2) and its interquartile values (Q1 and Q3).

Results: The search identified 92 potentially useful studies. Of these, 81 were discarded, and then remained 11 studies to be included. One out of 11 studies is an analytic case-control design. Rest are retrospective case series. Related mortality median was 0 (Q25=0 y Q75=28,57%).

Conclusion: Although the available evidence is scarce and of low quality, it suggests that clinical course of this condition does not always lead to high mortality rates.

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