Vol. 35 No. 1 (2018): February
Original Article

Factors associated to survival in patients with HIV-TB in the Department of Infectious Diseases of the Arzobispo Loayza National Hospital, Perú, since 2004 to 2012

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  • Brenda Gamboa-Acuña,
  • Rayza Guillén-Zambrano,
  • Grecia Lizzetti-Mendoza,
  • Alonso Soto,
  • Aldo Lucchetti-Rodríguez
Brenda Gamboa-Acuña
Universidad Peruana de Ciencias Aplicadas
Rayza Guillén-Zambrano
Universidad Peruana de Ciencias Aplicadas
Grecia Lizzetti-Mendoza
Universidad Peruana de Ciencias Aplicadas
Alonso Soto
Universidad Peruana de Ciencias Aplicadas; Hospital Nacional Hipólito Unánue
Aldo Lucchetti-Rodríguez
Hospital Nacional Arzobispo Loayza

Published 2018-02-28

Keywords

How to Cite

1.
Gamboa-Acuña B, Guillén-Zambrano R, Lizzetti-Mendoza G, Soto A, Lucchetti-Rodríguez A. Factors associated to survival in patients with HIV-TB in the Department of Infectious Diseases of the Arzobispo Loayza National Hospital, Perú, since 2004 to 2012. Rev. Chilena. Infectol. [Internet]. 2018 Feb. 28 [cited 2025 Nov. 23];35(1). Available from: https://revinf.cl/index.php/revinf/article/view/21

Copyright (c) 2018 Brenda Gamboa-Acuña, Rayza Guillén-Zambrano, Grecia Lizzetti-Mendoza, Alonso Soto, Aldo Lucchetti-Rodríguez

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Background: The main cause of death in HIV patients is tuberculosis (TB). However, few Latin American studies have evaluated the prognosis of patients with coinfection. Aim: To determine the factors associated with survival in patients with HIV-TB coinfection treated at a Peruvian referral hospital. Methods: A retrospective cohort study was performed based on clinical records of patients treated at the Department of Infectious Diseases in the Arzobispo Loayza National Hospital from 2004 to 2012. Survival was assessed using the Kaplan-Meier estimator and Cox Proportional Hazard Model. Results: From 315 patients, 82 died during the follow-up. The mean of follow for each patient was 730 days. The multivariate analysis showed that receiving HAART (HR: 0,31; IC: 0,20-0,50; p < 0,01) and having more weight (HR: 0,96; IC 0,94–0,98; p < 0,01) when the coinfection was diagnosed, were protective factors; while having a pathology different from TB (HR: 1,88; IC: 1,19-2,98; p < 0,01), age in years (HR: 1,76; IC: 1,12-2,74; p ≤ 0,01) and being hospitalized when diagnosed with TB (HR: 1,69; IC 1,02-2,80; p < 0,04) were associated with lower survival. Discussion: Receiving HAART and having more weight when the coinfection is diagnosed were associated with a higher chance of survival.
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