Antimicrobial Therapy Committee of Infectious Diseases Chilean Society, Practical guideline on the treatment of Gram negative infections
Published 2024-11-04
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Copyright (c) 2024 Daniela Pavez Azurmendi, Catalina Gutiérrez Ruiz, Loreto Rojas Wettig, Mirta Acuña Ávila, Dona Benadof Fuentes, Regina Perez Perez, Ruth Rosales Chacón, Claudio González Muñoz, Francisco Silva Ojeda, Felipe Bravo Bravo, José Miguel Arancibia Henriquez, Jorge Amador, Luis Bavestrello Fernandez

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Abstract
Bacterial resistance constitutes a growing public health problem worldwide, causing 5 million deaths and projecting to rise to 10 million by 2050, unless a global response is established to contain its advance. It is associated with greater morbidity and mortality and economic burden and occurs more frequently in hospital environments, especially in critical units, where Gram-negative bacilli are the most frequently isolated. The objective of this article is to provide evidence-based recommendations on the clinical management of Gram-negative bacterial infections.