Vol. 35 No. 5 (2018): October
Clinical Expreience

Late onset neonatal sepsis in an intensive care neonatal unit: etiological agents and most frequent location

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  • Gloria Celeste Samudio,
  • Ruth Monzón,
  • Lidia María Ortiz,
  • Gladys Maribel Godoy
Gloria Celeste Samudio
Hospital Nacional de Itaugua Guazu; Ministerio de Salud Pública y Bienestar Social
Ruth Monzón
Hospital Nacional de Itaugua Guazu; Ministerio de Salud Pública y Bienestar Social
Lidia María Ortiz
Hospital Nacional de Itaugua Guazu; Ministerio de Salud Pública y Bienestar Social
Gladys Maribel Godoy
Hospital Nacional de Itaugua Guazu; Ministerio de Salud Pública y Bienestar Social

Published 2018-11-25

Keywords

How to Cite

1.
Samudio GC, Monzón R, Ortiz LM, Godoy GM. Late onset neonatal sepsis in an intensive care neonatal unit: etiological agents and most frequent location. Rev. Chilena. Infectol. [Internet]. 2018 Nov. 25 [cited 2025 Nov. 21];35(5). Available from: https://revinf.cl/index.php/revinf/article/view/253

Copyright (c) 2018 Gloria Celeste Samudio, Ruth Monzón, Lidia María Ortiz, Gladys Maribel Godoy

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Introduction: Nosocomial neonatal sepsis (NNS) is a frequent entity in intensive care units, causing great morbidity and mortality. The most frequent site is blood, followed by lungs and urine. Objective: To know the etiology and most frequent localization of infection in the NNS. Population, Material and Methods: Cross sectional study, from January to December 2015, performed in a teaching hospital. All newborns infants were included. Results: 70 patients were included, 88 episodes of NNS were analyzed. The most frequent localization was bacteremia in 40% of cases, followed by urinary tract infection and VAP in 25% respectively. The bacteria most frequently isolated were staphylococci of different types, followed by multiresistant Acinetobacter. The CNS involvement was 32%. Mortality was 34%, rising up to 50% with a second episode of NNS. The empirical therapy of choice was vancomycin and carbapenem, adjusting to antibiogram. Conclusions: The most frequent infection was bacteremia, mainly by staphylococci resistant to methicillin. CNS involvement was elevated, as well as mortality
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