Vol. 36 No. 6 (2019): Diciembre
Clinical Case

First isolation de Candida auris in Chile

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  • María Victoria Moreno López,
  • María Elvira Simian,
  • Javier Villarroel,
  • Luz María Fuenzalida,
  • María Fernanda Yarad,
  • Andrés Soto,
  • Verónica Silva,
  • Ximena Pimentel
María Victoria Moreno López
Hospital del Salvador
Bio
María Elvira Simian
Facultad de Medicina, Universidad de Chile, Chile.
Javier Villarroel
Hospital del Salvador
Luz María Fuenzalida
Hospital del Salvador
María Fernanda Yarad
Hospital del Salvador
Andrés Soto
Hospital del Salvador
Verónica Silva
Hospital del Salvador
Ximena Pimentel
Hospital Salvador

Published 2020-01-18

Keywords

How to Cite

1.
Moreno López MV, Simian ME, Villarroel J, Fuenzalida LM, Yarad MF, Soto A, Silva V, Pimentel X. First isolation de Candida auris in Chile. Rev. Chilena. Infectol. [Internet]. 2020 Jan. 18 [cited 2026 May 13];36(6). Available from: https://revinf.cl/index.php/revinf/article/view/463

Copyright (c) 2020 María Victoria Moreno López, María Elvira Simian, Javier Villarroel, Luz María Fuenzalida, María Fernanda Yarad, Andrés Soto, Verónica Silva, Ximena Pimentel

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Candida auris is an emerging multi-drug-resistant fungus that is rapidly spreading worldwide. Since the first reports in 2009, many isolates across five continents have been identified as agents of hospital-associated infections. Independent and simultaneous outbreaks of C. auris are becoming a major concern for healthcare and scientific community. Moreover, laboratory misidentification and multi-drug-resistant profiles, rarely observed for other non-albicans Candida species, result in difficult eradication and frequent therapeutic failures of C. auris infections. In this article we present the first case of isolation of a strain of C. auris at a hospital in Santiago, in a patient coming from India, who was admitted for treatment of diabetic foot complications. The strain was recovered from a tissue culture and identified by VITEK® 2 Compact. The accurate identification of C. auris was confirmed by means of MALDI-TOF MS and DNA sequence analysis. The isolate was resistant to fluconazole, retaining only susceptibility to amphotericin and caspofungin with MIC breakpoints recommended by CDC. The emergence of C. auris is alarming because the mode of transmission within the healthcare environment is not clear and is likely to be multifactorial.
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