Vol. 37 No. 2 (2020): April
Clinical Expreience

Osteo-articular infections by Kingella kingae in children in a highly complex pediatric hospital: epidemiology and associated factors

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  • M Guadalupe Perez,
  • Eva Veronica Deschutter,
  • Maria Elena Venuta,
  • Soledad Mussini,
  • Adela Isasmendi,
  • Vanesa Reijtman,
  • M Laura Tripodi,
  • Sofia Abel,
  • Agustina Ponzone,
  • Alejandra Mastroianni Mastroianni,
  • Jose Luis Pinheiro,
  • M Eva Garcia,
  • Rosa Bologna,
  • Maria Teresa Rosanova
M Guadalupe Perez
Hospital de Pediatria Prof dr Juan P Garrahan

Published 2020-05-17

Keywords

How to Cite

1.
Perez MG, Deschutter EV, Venuta ME, Mussini S, Isasmendi A, Reijtman V, Tripodi ML, Abel S, Ponzone A, Mastroianni AM, Pinheiro JL, Garcia ME, Bologna R, Rosanova MT. Osteo-articular infections by Kingella kingae in children in a highly complex pediatric hospital: epidemiology and associated factors. Rev. Chilena. Infectol. [Internet]. 2020 May 17 [cited 2025 Nov. 15];37(2). Available from: https://revinf.cl/index.php/revinf/article/view/587

Copyright (c) 2020 M Guadalupe Perez, Eva Veronica Deschutter, Maria Elena Venuta, Soledad Mussini, Adela Isasmendi, Vanesa Reijtman, M Laura Tripodi, Sofia Abel, Agustina Ponzone, Alejandra Mastroianni Mastroianni, Jose Luis Pinheiro, M Eva Garcia, Rosa Bologna, Maria Teresa Rosanova

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Background: The epidemiology of osteoarticular infections (IOA) has changed in recent years. The incidence of Kingella kingae in Latin America is unknown.

Aims: To describe the epidemiology in patients with IOA in a children hospital. To estimate the incidence of IOA due to K. kingae and compare with other etiologies.

Methods: Prospective cohort. Patients older than 1 month hospitalized between March, 1th 2017 and February, 28th 2019 with suspected IOA and diagnostic procedure (biopsy or arthrocentesis) were included. STATA 13 was used.

Results: n: 84 patients. The etiology was identified in 58 patients (69.1%). Staphylococus aureus predominated (n: 44; 52.4%) and K. kingae (n: 9; 10.8%). In the period studied, the incidence of IOA by K. kingae was 10.8 cases per 100 hospitalized IOA. In multivariate analysis, age less than 4 years (OR 13.8, 95% CI 5.5-82.7), recent respiratory symptoms (OR 5.7, 95% CI 3.5-31.6, p 0.04) and normalization before the fifth day of C-reactive protein (CRP) (OR 3.38 95% CI 1.8-16.3, p 0.01) were associated with IOA by K. kingae.

Conclusions: In this cohort of children the incidence of K. kingae was 10.8 cases per 100 IOA. Kingella kingae represented the second documented etiology, after S. aureus. Age under 4 years, recent respiratory symptoms and normalization before the fifth day of quantitative CRP were statistically associated with IOA by K. kingae.

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