Association of nutritional status and clinical factors with tuberculosis related death in Colombia

Abstract

Background: Studies link tuberculosis (TB) with sociodemographic characteristics of human populations and the presence of comorbidities in these patients. Today one of the most important comorbidities in Colombia is malnutrition; it would be important to verify its relationship with the mortality issue independently of the other variables present in the patients. Aim: To determine the association of nutritional status and the main clinical factors with death related to TB in Colombia. Methods: A descriptive cross-sectional study was carried out in a total of 12,778 patients who met defined inclusion and exclusion criteria Bivariate analysis was performed and a multivariate logistic regression model was constructed. Results: The sociodemographic variables associated with death from TB were: male sex (OR 1.49 95% CI 1.14-1.95); indigenous population (OR 1.76 95% CI 1.09-2.85). The clinical variables: low weight (OR 1.32 95% CI 1.04-1.68) and clothing for HIV (OR 1.46 95% CI 1.06-2.00) were related to mortality and having forms of extrapulmonary TB were as a protective factor (OR 0.44 95% CI 0.29-0.67) Conclusions: In patients with low weight, HIV coinfection, male sex, and indigenous population presented a high risk of death from TB, making it necessary to implement comprehensive approach strategies.