Vol. 35 No. 4 (2018): Agosto
Clinical Expreience

Incidence of group B streptococcal early-onset sepsis in infants born at Centro Hospitalario Pereira Rossell between 2007-2015.

PDF (Español (España))
  • Tamara I. Herrera,
  • Micaela Murillo,
  • Juan Pablo Gesuele,
  • Mario Moraes,
  • María Inés Mota,
  • Claudia Gutiérrez,
  • Adriana Varela,
  • Gabriela Algorta
Tamara I. Herrera
Centro Hospitalario Pereira Rossell
Micaela Murillo
Centro Hospitalario Pereira Rossell
Juan Pablo Gesuele
Centro Hospitalario Pereira Rossell
Mario Moraes
Centro Hospitalario Pereira Rossell
María Inés Mota
Centro Hospitalario Pereira Rossell
Claudia Gutiérrez
Centro Hospitalario Pereira Rossell
Adriana Varela
Centro Hospitalario Pereira Rossell
Gabriela Algorta
Centro Hospitalario Pereira Rossell

Published 2018-09-17

Keywords

How to Cite

1.
Herrera TI, Murillo M, Gesuele JP, Moraes M, Mota MI, Gutiérrez C, Varela A, Algorta G. Incidence of group B streptococcal early-onset sepsis in infants born at Centro Hospitalario Pereira Rossell between 2007-2015. Rev. Chilena. Infectol. [Internet]. 2018 Sep. 17 [cited 2025 Nov. 15];35(4). Available from: https://revinf.cl/index.php/revinf/article/view/176

Copyright (c) 2018 Tamara I. Herrera, Micaela Murillo, Juan Pablo Gesuele, Mario Moraes, María Inés Mota, Claudia Gutiérrez, Adriana Varela, Gabriela Algorta

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Background: Group B Streptococcus (GBS) disease remains the leading cause of early-onset sepsis (EOS) in developed countries despite effective prophylaxis strategies. Aims: To describe the incidence, clinical features and mortality of GBS EOS in infants born at Centro Hospitalario Pereira Rossell (CHPR) and analyse failure of adherence to prevention strategies. Methods: Retrospective review of EOS cases between 2007 and 2015 collected from the bacteriology laboratory database. Results: Fifteen cases of GBS EOS were identified, with an incidence of 0.23% during the study period. Intrapartum antibiotic prophylaxis (IAP) was not administered in any of the cases. All infants were symptomatic within the first 15 hours of life, mainly due to respiratory signs (80%). In one case, GBS was isolated from spinal fluid. Mortality rate was 20%. All deaths occurred in the first 24 hours of life, corresponding two thirds to preterm infants. Conclusion: The incidence of GBS EOS at CHPR was similar to other centers where IAP is implemented. Better adherence to prophylaxis strategies could reduce the incidence.
PDF (Español (España))